Sunday, January 3, 2010

Are you taking a Placebo?

For those heart patients who are taking Plavix blood thinner to help their heart work easier but are also taking acid-reducing PPI Nexium for their GERD (gastric reflux)or any of these like Tagamet, Prozac, then they might as well be taking a Placebo.

The drugs may make the anti-clotting drug Plavix dangerously less effective which means 3.58 times greater risk for major adverse cardiovascular events such as death, heart attack, and stroke. This risk was published in December 22, 2008.
http://content.nejm.org/cgi/content/abstract/NEJMoa0808227v1..

This risk was again brought to media attention in March 2009.
http://www.medicinenet.com/script/main/art.asp?articlekey=98231

The FDA eventually issued this warning on Nov 17.
http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm190848

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